Association between Dietary Patterns and Non-alcoholic Fatty Liver Disease: Results from a Case-Control Study

Association between Dietary Patterns and Non-alcoholic Fatty Liver Disease: Results from a Case-Control Study


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نویسندگان: هلدا توتونچی , مریم ثقفی اصل , محمد اصغری جعفرآبادی , علیرضا استاد رحیمی

کلمات کلیدی: Adult population, Dietary patterns, Factor analysis, Non-alcoholic fatty liver (NAFLD)

نشریه: 3011 , 1 , 24 , 2021

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نویسنده ثبت کننده مقاله علیرضا استاد رحیمی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات علوم تغذیه
کد مقاله 76235
عنوان فارسی مقاله Association between Dietary Patterns and Non-alcoholic Fatty Liver Disease: Results from a Case-Control Study
عنوان لاتین مقاله Association between Dietary Patterns and Non-alcoholic Fatty Liver Disease: Results from a Case-Control Study
ناشر 4
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Abstract Background: This study aimed to investigate the association between dietary patterns and non-alcoholic fatty liver disease (NAFLD) among Iranian adults. Methods: This case-control study was conducted on 210 subjects. NAFLD diagnosis was made by ultrasound examination. Anthropometric measures, physical activity, fasting serum levels of glucose, alanine aminotransferase (ALT), aspartate aminotransferase, and lipid profile were assessed. A three-day food diary was used to assess dietary intakes of the subjects. Dietary patterns were determined using factor analysis. To determine the relationship between dietary patterns and NAFLD, multivariable-adjusted odds ratio (OR) obtained from the logistic regression analysis was used. Results: Two dietary patterns were extracted as follows: vegetables, legumes, fruits, and low-fat dairy products (VLFD) ; and sweet, hydrogenated fat, red and processed meat, and soft drink (SHMS) dietary patterns. By taking all possible confounders into account, the VLFD dietary pattern was found to be significantly related to lower odds of NAFLD, while the SHMS dietary pattern was independently related to higher odds of NAFLD (P < 0.05). Among major food groups, high consumption of processed meat, hydrogenated fats, sweets and desserts, and soft drinks was positively related to NAFLD (P < 0.05), whereas vegetable consumption exhibited a protective role against NAFLD (P = 0.01). Conclusion: The VLFD dietary pattern was associated with reduced likelihood of having NAFLD, while the SHMS dietary pattern was associated with higher likelihood. Therefore, the VLFD dietary pattern might be useful in the nutritional strategies for NAFLD patients. Further studies with larger sample sizes and prospective design are warranted. Keywords: Adult population, Dietary patterns, Factor analysis, Non-alcoholic fatty liver (NAFLD) Cite this article as: Tutunchi H, Saghafi-Asl M, Asghari-Jafarabadi M, Ostadrahimi A. Association between dietary patterns and non-alcoholic fatty liver disease: results from a case-control study. Arch Iran Med. 2021;24(1):35–42. doi: 10.34172/aim.2021.06.

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نویسنده نفر چندم مقاله
هلدا توتونچیاول
مریم ثقفی اصلدوم
محمد اصغری جعفرآبادیسوم
علیرضا استاد رحیمیچهارم

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Archives of Iranian Medicine.pdf1400/04/13267838دانلود