چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Severe neutropenia subsequent to myelosuppression after chemotherapy increases the risk of bacterial and fungal infections. Routine and repeated determination of blood neutrophil counts is necessary for patients after chemotherapy for early diagnosis of neutropenia. The aim of the present study was to determine the correlation between oral rinse and peripheral blood neutrophil counts in patients with acute myeloid leukemia, referring to Tabriz Shahid Ghazi Hospital. The present study was carried out on 39 acute myeloid leukemia (AML) patients. One day before chemotherapy and 7, 14 and 21 days after chemotherapy, oral rinse and peripheral blood samples were taken from the patients. The peripheral blood sample neutrophil counts were determined using the H1 test device and oral rinse neutrophil counts were determined by acridine orange staining technique under a light microscope and also by the H1 device. Data were analyzed with SPSS 17. The results showed significant differences in peripheral blood neutrophil counts one day before chemotherapy and 7, 14 and 21 days after chemotherapy (P<0.001). There were significant differences in oral rinse neutrophil counts between the same intervals with both techniques (P<0.001). Furthermore, there was a correlation between the peripheral blood and oral rinse neutrophil counts with the use of the H1 equipment and under the light microscope. The results of this study showed a significant correlation between oral rinse and peripheral blood neutrophil counts in the subjects. Therefore, the oral rinse technique can be used as a non-invasive technique to monitor neutrophil counts in patients with AML after chemotherapy. |
| نویسنده | نفر چندم مقاله |
|---|---|
| رضا پورعباس خیرالدین | دوم |
| سپیده وثوق حسینی | سوم |
| زهره صناعت | چهارم |
| پریا اماموردیزاده | پنجم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| article.pdf | 1400/04/11 | 202425 | دانلود |
