| نویسنده ثبت کننده مقاله | یگانه راستگاررضایی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده علوم نوین پزشکی |
| کد مقاله | 76209 |
| عنوان فارسی مقاله | Cytokines as biomarkers for embryo selection |
| عنوان لاتین مقاله | Cytokines as biomarkers for embryo selection |
| نوع ارائه | پوستر |
| عنوان کنگره / همایش | 9th Yazd International Congress and Student Award on Reproductive Medicine |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | Iran (Islamic Republic) |
| شهر محل برگزاری کنگره/ همایش | Yazd |
| سال انتشار/ ارائه شمسی | 1400 |
| سال انتشار/ارائه میلادی | 2021 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1400/02/23 الی 1400/02/25 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://web.ssu.ac.ir/en/240 |
| آدرس علمی (Affiliation) نویسنده متقاضی | Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran. |
| نویسنده | نفر چندم مقاله |
|---|---|
| حامد حاجی پور | دوم |
| یگانه راستگاررضایی | سوم |
| زینب لطیفی | پنجم |
| حمیدرضا نجابتی | ششم |
| لعیا فرزدی | هفتم |
| امیر فتاحی | هشتم |
| محمد نوری | نهم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Background: Studies have shown that the morphological assessments to select the best embryo for transfer could not provide satisfactory outcomes. Therefore, many studies have been conducted to find predictive biomarkers that can distinguish embryos with high implantation potential. Objective: In the current study, we comprehensively reviewed the possibility of using embryo-secreted cytokines as potential biomarkers for embryo selection in assisted reproductive technology. Materials and Methods: The present review involved published research articles that have investigated cytokines in the embryo secretome. A search in Google Scholar and PubMed was performed with no limitation on the date of publication using a combination of the following search terms: “secretome”, “culture media”, and “cytokine (s)”. Results: It can be postulated that the embryo secretome can well reflect the embryo condition. Since the immune system has an indubitable role in implantation and also the immunological factors are involved in the embryo-endometrial crosstalk, the embryo-secreted cytokines can be used as potential biomarkers. Conclusion: In conclusion, the following three points should take into consideration while using embryo-secreted factors as biomarkers: 1) The culture media should be evaluated at a certain stage of embryo development (e.g. cleavage and blastocyst), 2) The measurement method should be able to detect very small levels of factors, and 3) Changing in the concentration of several embryo-secreted factors in combination should be evaluated to propose an appropriate embryo selection method. |
| کلمات کلیدی | Embryo, Cytokines, Implantation, Secretome, Culture media. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 2724.pdf | 1400/04/11 | 192136 | دانلود |
| 2724.png | 1400/04/11 | 479533 | دانلود |