Effect of Dexmedetomidine on Blood Pressure in Patients with Hypertension after Emergency Laparotomy for Trauma: A Randomized Double-blind Clinical Trial

Effect of Dexmedetomidine on Blood Pressure in Patients with Hypertension after Emergency Laparotomy for Trauma: A Randomized Double-blind Clinical Trial


چاپ صفحه
پژوهان
صفحه نخست سامانه
چکیده مقاله
چکیده مقاله
نویسندگان
نویسندگان
دانلود مقاله
دانلود مقاله
دانشگاه علوم پزشکی تبریز
دانشگاه علوم پزشکی تبریز

نویسندگان: رضا موثقی گرگری , حسن محمدی پور انوری

کلمات کلیدی: Keywords Emergency Laparotomy Trauma Blood Pressure Dexmedetomidine

نشریه: 33898 , 2 , 26 , 2021

اطلاعات کلی مقاله
hide/show

نویسنده ثبت کننده مقاله حسن محمدی پور انوری
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه دانشکده پیراپزشکی
کد مقاله 75842
عنوان فارسی مقاله Effect of Dexmedetomidine on Blood Pressure in Patients with Hypertension after Emergency Laparotomy for Trauma: A Randomized Double-blind Clinical Trial
عنوان لاتین مقاله Effect of Dexmedetomidine on Blood Pressure in Patients with Hypertension after Emergency Laparotomy for Trauma: A Randomized Double-blind Clinical Trial
ناشر 2
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

خلاصه مقاله
hide/show

Abstract Background: Patients with a history of hypertension experience higher postoperative complications than healthy individuals. The frequency of such complications is also higher in emergency patients than elective ones; therefore, it seems that preventive measures are essential. Objectives: The present study aimed at determining the effect of dexmedetomidine on blood pressure in patients with hypertension after emergency laparotomy for trauma. Methods: The present study was a randomized, double-blind clinical trial performed from 2019 to 2020 on patients with a history of hypertension undergoing emergency laparotomy. Patients received the intervention 15 minutes before surgery (the intervention group: intravenous (iv) dexmedetomidine and the control group: normal saline), and the intensity of the pain(VAS), agitation(RASS), and blood pressure were measured and compared at different time points. Data were compared using SPSS software (version 21) by t-test and Chi-square tests considering a significance level of <0.05. Results: There were statistically significant differences between the two groups just after the drug infusion and at all studied time points (p <0.05), so that the intervention group had more stable blood pressure. Pain intensity (p <0.05) and the degree of agitation (p <0.05) in the intervention group were significantly lower than that in the control group at all studied time points. Conclusion: Dexmedetomidine infusion leads to a stabilization of blood pressure during surgery and after surgery, pain relief, and agitation in patients with hypertension undergoing emergency laparotomy for trauma.

نویسندگان
hide/show

نویسنده نفر چندم مقاله
رضا موثقی گرگریاول
حسن محمدی پور انوریدوم

لینک دانلود مقاله
hide/show

نام فایل تاریخ درج فایل اندازه فایل دانلود
0101.pdf1400/02/25844017دانلود