چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Recently, using antibiotic-free nanofbrous mats in wound healing has signifcant attention for infection cure after tissue injuries as a result of no drug resistance. Honey is a natural wound-healing agent that has been reintroduced to clinical wound treatment because of its good antioxidant and antibacterial properties. In this work, honey in various blending ratios was incorporated into the ethylcellulose (EC)/gum tragacanth (GT) electrospun nanofbrous (EGH NF) mat to develop an effective wound covering biomaterial. The physicochemical and biological characteristics of fabricated EGH NFs were evaluated by several methods. The effect of honey and the honey concentration enhancement (from 5 wt% to 20 wt%) was studied on the various properties of the NFs. The obtained results presented suitable antibacterial properties, enhanced antioxidant activity, improved degradation ability, increased mechanical features, proper cell growth, attachment, and proliferation against NIH-3 T3 fbroblast cells. The cytotoxicity assay showed the biocompatibility and non-cytotoxicity of the developed NF mats. Therefore, these achieved results suggested that the developed EGH NFs can be a promising candidate for wound dressing applications. |
| نویسنده | نفر چندم مقاله |
|---|---|
| مرجان قربانی | اول |
| محمدرضا رشیدی شاهگلی | سوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Ghorbani,2021,79.pdf | 1400/02/11 | 7097223 | دانلود |
