چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Intricacy in treatment and diagnosis of breast cancer has been an obstacle due to genotype and phenotype heterogeneity. Understanding of non-genetic heterogeneity mechanisms along with considering role of genetic heterogeneity may fill the gaps in landscape painting of heterogeneity. The main factors contribute to non-genetic heterogeneity including: transcriptional pulsing/bursting or discontinuous transcriptions, stochastic partitioning of components at cell division and various signal transduction from tumor ecosystem. Throughout this review, we desired to provide a conceptual framework focused on non-genetic heterogeneity, which has been intended to offer insight into prediction, diagnosis and treatment of breast cancer. |
| نویسنده | نفر چندم مقاله |
|---|---|
| ندا برزگر باروق | اول |
| کبری ولائی | پنجم |
| فخرالسادات سجادیان | دوم |
| نازیلا جلیل زاده | سوم |
| هاجر شفائی | چهارم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| BarzgarBarough2021_Article_UnderstandingBreastCancerHeter.pdf | 1400/04/20 | 1065455 | دانلود |
