چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| ype I interferons (IFNs), are considered as a main host immune system cytokines effector against infectious virus. In addition to ǁiǁnnatǁeimǁmunerecepǁtorbacǁterialligǁands and/or bactǁerial infections. Furthermore, thǁe development oǁf kinds IǁFǁNs are aǁlsǁo triggered, suggesting a wider physiological function fǁor those cyǁtokǁinesiǁnhomǁeostaisi and hǁostproteǁctionthǁan initially expected. Results: To recognize both structural divergence and sequence various bioinformatics methods were used. Initial sequence analysis of IFNß1 showed that they shared with human over 70% similarity and some identity like Rhesus monkey, pig , domestic cat ,for dog. With few exceptions, sequences showed a high degree of sequence preservation. The physico-chemical analysis indicated a large developmental difference between humans and others and an estimate of 39% to 42% of hydrophobic residues. Four human mammals house mouse pig Norway rat have various Pfam types. The secondary structure of IFNß1 composed of ranǁdomcoǁil, ExvǁtendedstrǁandaǁndAlǁphaheǁlix. Conclusions: Depending oǁnthǁeresǁults collected, which maybe assumed thǁat in these mammalian species IFNß1 has the same counterpart, highly retained and functional similarities. |
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| سپیده پرویزپور | دوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
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| 3128-Article Text-5783-1-10-20200614.pdf | 1400/01/22 | 846135 | دانلود |
