چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| A synchronous fluorescence spectroscopy (SFS) nanoprobe is developed for the determination of vancomycin in exhaled breath condensate (EBC) samples. The synthesized nanoprobe is copper nanoclusters (Cu NCs) and its SFS peak is located at 405 nm with ∆λ=80. The affinity of Cu NCs to complex formation with vancomycin results in blocking non-radiative e-/h+ recombination defect sites on the surface of NCs and consequently enhancing the SFS signal intensity. Central composite design and response surface methodology were used for the optimization of reaction conditions. Under the optimized conditions, a linear relationship was found between the SFS intensity and the concentration of vancomycin in the range of 0.1−8 µg mL−1. The validated method was applied for the determination of vancomycin in EBC of newborns receiving vancomycin treatment. |
| نویسنده | نفر چندم مقاله |
|---|---|
| الهه رحیم پور | اول |
| مریم خوب نسب جعفری | دوم |
| محمدباقر حسینی | سوم |
| ابوالقاسم جویبان | چهارم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| C.pdf | 1400/02/22 | 1201492 | دانلود |
