چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| سعید چارسوئی | اول |
| عنوان | متن |
|---|---|
| کلمات کلیدی | sleep,epilepsy,seizure |
| خلاصه مقاله | Although the close relationship between sleep and epilepsy is evident, the mechanisms underlying this connection remain unknown. In general, sleep facilitates epileptic activity and seizures.However, there are some specific epilepsy syndromes which have a marked tendency to manifest only or predominantly during sleep, or after arousal from sleep.The American Academy of Sleep Medicine (AASM) provided diagnostic criteria for sleep-related epilepsy : sleep-related epilepsy as epilepsy in which ‘‘70% of the epileptic episodes occur during sleep.’’ Janz classified epilepsies into :‘awakening’ (seizures in the first 2 h after awakening, 34%) ‘sleep’ (during sleep, 45%) ‘diffuse’ (21%) .Janz further noted that the ‘awakening’ epilepsies were more likely to be idiopathic and generalized than symptomatic, while ‘diffuse’ epilepsies tended to be symptomatic. Frontal lobe seizures more commonly begin during sleep Temporal lobe seizures begin more commonly awake .Temporal and occipital lobe seizures in particular generalize more during sleep whereas frontal lobe seizures less commonly generalize. Although the mechanism remains unclear, effect of sleep deprivation on epilepsy has been confirmed in many studies. One episode of all-night activity frequently induces seizures in patients who have not experienced a seizure for a long time. Therefore, patients with epilepsy are generally advised to maintain good sleep habits. The patients are deprived of sleep before EEG monitoring to increase the chance of seizure detection during the EEG. Patients with epilepsy frequently have daytime somnolence, sleep fragmentation, and poor sleep quality, especially those with poor seizure control. Sleep disturbances in patients with epilepsy are about twice as common as they are in healthy controls . Antiepileptic treatment can affect sleep. Some antiepileptic drugs are associated with excessive daytime sleepiness. Valproate and high doses of levetiracetam also cause sleepiness, while Topiramate and zonisamide do not . Antiepileptic drugs may also alter sleep architecture:Phenytoin increasing N1 and decreasing N3,Valproate increases N1 ,Gabapentin increases N3 but Carbamazepine and Lamotrigine do not alter sleep architectur |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| govahi.jpg | 1399/12/12 | 1453839 | دانلود |
| Sleep abstract.docx | 1399/12/12 | 13262 | دانلود |
| govahi 1.pdf | 1399/12/12 | 73293 | دانلود |
