چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| امیررضا جهانشاهی | اول |
| عنوان | متن |
|---|---|
| خلاصه مقاله | MRI is nowadays extends beyond its traditional role of excluding neurosurgical lesions and may support the diagnosis of specific neurodegenerative disorders and sometimes radiological findings are necessary to confirm the diagnosis. An MR-study of a patient suspected of having dementia must be assessed in a standardized way,First of all, treatable diseases like subdural hematomas, tumors and hydrocephalus need to be excluded and next we should look for signs of specific dementias which include Alzheimer's disease (AD), Frontotemporal Lobar Degeneration (FTLD), Vascular Dementia (VaD) and Dementia with Lewy bodies (DLB). standardized assessment of the MR findings in a patient suspected of having a cognitive disorder includes: 1-GCA-scale for Global Cortical Atrophy 2-MTA-scale for Medial Temporal lobe Atrophy 3-Koedam score for parietal atrophy 4-Fazekas scale for WM lesions 5-and at last step,looking for strategic infarcts GCA-scale for Global Cortical Atrophy is mean score for cortical atrophy throughout the complete cerebrum but it is important to notice that Until you have a good sense of what the normal brain looks like at all ages, be hesitate to label brain atrophic and there is a spectrum of normal brain parenchyma for any age and also we have some Causes of reversible atrophy which include dehydration/shock, Starvation/anorexia, Steroid use, Alcoholism(limited reversibility), Chemotherapy,Marijuana and Radiation therapy. MTA-scale is used for Medial Temporal lobe Atrophy and should be rated on coronal T1-weighted images and Select a slice through the corpus of the hippocampus, at the level of the anterior pons. Fazekas scale provides an overall impression of the presence of WMH in the entire brain.It is best scored on transverse FLAIR or T2-weighted images.this scale predicts future disability in elderly. Strategic infarctions are infarctions in areas that are crucial for normal cognitive functioning of the brain and best seen on transverse FAIR and T2W sequences. Koedam score is used for Parietal Atrophy and it is important to notice that In addition to medial temporal lobe atrophy, parietal atrophy also has a positive predictive value in the diagnosis of AD.this assessment is done in sagittal, coronal and axial planes |
| کلمات کلیدی | dementia -hypocampus-MRI |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| My Doc-349387.jpg | 1399/11/26 | 816081 | دانلود |
| senile2.JPG | 1399/12/09 | 66215 | دانلود |
