| Acute ischemic stroke (AIS), is the second global cause of death after cardiovascular diseases, accounts for
80–85% of cerebrovascular disease. Stroke diagnosis could be challenging in the acute phase. Detection of
biomarkers for evaluating the prognosis of diseases is essential for improving personalized treatment and
decreasing mortality. At the present time, the absence of a broadly existing and rapid diagnostic test is an
important limitation in the evaluation and treatment of diseases. The use of a biomarker-based diagnostic attitude has been confirmed very valuable in acute coronary syndromes, which has been promoted in acute stroke to help
early management decisions. Over the past decade, different detection procedures have developed for the
assessment of human cardiac troponins (cTnI). This review emphasizes summarizing optical, and electrochemical biosensors for the detection of cTnI, brain natriuretic peptide (BNP), and neuron-specific enolase (NSE)
as a critical biomarker in stroke |