یک روش سریع پلاروگرافی الکترود جیوه قطره ای برای تعیین مقدار سطح خونی سرب در افراد مسموم شده با سرب
A rapid Mercury Droplet Electrode Polarography Method Determination Of Blood Lead Level in Lead Poisoned people
نویسندگان: علی اصغر حمیدی , گلریز حسینی , جلال حنائی , علی استادی
کلمات کلیدی: Mercury Droplet Electrode, Polarography , Blood Lead Level, Lead Poisoned people
نشریه: 45030 , 4 , 71 , 2020
| نویسنده ثبت کننده مقاله |
علی اصغر حمیدی |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
دانشکده داروسازی |
| کد مقاله |
75023 |
| عنوان فارسی مقاله |
یک روش سریع پلاروگرافی الکترود جیوه قطره ای برای تعیین مقدار سطح خونی سرب در افراد مسموم شده با سرب |
| عنوان لاتین مقاله |
A rapid Mercury Droplet Electrode Polarography Method Determination Of Blood Lead Level in Lead Poisoned people |
| ناشر |
6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
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| Abstract:
Background: Lead is a hazardous heavy metal, which causes many problems in the human body. Unfortunately, recent reports showed that smugglers and opium sellers add lead to drugs during the production procedure in orther to increase its weight and cost.
Purpose: the aim of this study was development and a rapid and accurate method for measurement of blood lead levels (BLL) in the oral and inhaled opiate abuse people.
Methods: BLL in samples obtained from the oral and inhaled opium addicted patients referring to Sina Hospital in Tabriz, Iran, during 2017 was compared with healthy control group (N=15). The wet digestion method was used to prepare whole blood and Mercury Droplet Electrode Polarography (MDEP) method was utilized for measurement of the lead content of digested samples.
Results: Results showed that there were significant from oral (17.12±4.61ug/dl, p<0.0003) and inhaled (19.33±2.257 ug/dl p<0.0001) opium addicted groups in comparison with healthy control group (4.669±0.3367 ug/dl).
Conclusion: Based on the results of this study it was observed that BLL in opium addicted people needs to be measured as soon as possible. Furthermore, screening of blood lead concentrations in opium addicted peoplewith a rapid and accuratebMDEP metohde is very necessary and important. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| a-1293-6924.pdf | 1400/04/02 | 223551 | دانلود |