چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Background & aims: Metabolic syndrome (MetS) is a clinical disorder with widespread prevalence. In the current study, we aimed to investigate the association between serum soluble P-selectin, procalcitonin, transforming growth factor (TGF)-b and apo-proteins with the components of metabolic syndrome in obese individuals. Material and methods: Sixty two obese patients with MetS and sixty five obese apparently healthy controls were participated in the current caseecontrol study. The participants’ anthropometric assessments and systolic and diastolic blood pressure (SBP and DBP) were measured. Serum lipids and the concentrations of ox-LDL, P-selectin, procalcitonin, TGF-b and apo-proteins were measured with commercial ELIZA kits. Results: Serum TG and TC were significantly higher in obese subjects with MetS; while TGF-b, procalcitonin, apoprotein B and insulin concentrations were higher in obese non- MetS group. In obese subjects with MetS, procalcitonin was in positive association with ox-LDL and apoprotein-B was in positive association with HDL. In obese subjects without MetS, apoprotein eB was in positive association with WC and HDL and WC. Conclusion: The current study found several associations between serum lipids and PCT and serum apoproteins in obese individuals either with or without MetS. Further studies with large sample size are warranted to better elucidate the observed relationships and underlying mechanism. Trial registration: Not Applicable. |
| نویسنده | نفر چندم مقاله |
|---|---|
| مهدیه عباسعلیزاد فرهنگی | سوم |
| مهران مسگری عباسی | اول |
| مهسا محمودی نژاد | دوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| clinical espen.pdf | 1399/11/06 | 372902 | دانلود |
