چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | سولماز ملکی دیزج |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | مرکز تحقیقات لثه و دندان |
| کد مقاله | 74850 |
| عنوان فارسی مقاله | Nanostructured lipid carriers (NLC) delivering Punica granatum seed oil with antimicrobial activity against Staphylococcus epidermidis: production, characterization and in vitro studies |
| عنوان لاتین مقاله | Nanostructured lipid carriers (NLC) delivering Punica granatum seed oil with antimicrobial activity against Staphylococcus epidermidis: production, characterization and in vitro studies |
| نوع ارائه | پوستر |
| عنوان کنگره / همایش | The 17th International Congress of Immunology |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | China |
| شهر محل برگزاری کنگره/ همایش | Beijing |
| سال انتشار/ ارائه شمسی | 1398 |
| سال انتشار/ارائه میلادی | 2019 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1398/07/28 الی 1398/08/02 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://www.immunology.org/events/17th-international-congress-immunology-iuis-2019 |
| آدرس علمی (Affiliation) نویسنده متقاضی | Dental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, Iran, |
| نویسنده | نفر چندم مقاله |
|---|---|
| نازنین فتحی | اول |
| سولماز ملکی دیزج | دوم |
| حامد همیشه کار | سوم |
| فرزانه لطفی پور بناب | چهارم |
| عنوان | متن |
|---|---|
| کلمات کلیدی | Nanostructured lipid carriers,Punica granatum seed oil, Staphylococcus epidermidis |
| خلاصه مقاله | Staphylococcus epidermidis has been recognized as the most common cause of device-related infections that occur in hospitals and is thus recently known as an essential opportunistic pathogen. On the other hand, the antimicrobial effect of NLC associated products is an attractive topic for finding more effective agents. The main aim of this study was the preparation and characterization of nanostructured lipid carriers (NLCs) encapsulated with P. granatum seed oil and assessment of antimicrobial effect of this combination against Staphylococcus epidermidis. Particle size distribution, morphology, as well as physical stability of the optimized formulation, was organized by particle size analysis, X-ray diffraction (XRD), scanning electron microscopy, gas chromatography and hot melt homogenization method. MIC (Minimum inhibitory concentrations) of P. granatum seed oil -loaded NLCs were assessed and compared to seed oil emulsion of P. granatum against Staphylococcus epidermidis. NLCs loaded with seed oil of P. granatum were spherical shaped nanosize (102.1 nm) particles having a narrow size distribution (PDI = 0.268) and good physical stability following storage for 3 months. The results from XRD revealed that the seed oil of P. granatum had an amorphous form within nanoparticle matrix. Antibacterial assay showed that P. granatum seed oil-loaded NLCs displayed a significant in vitro antimicrobial activity than seed oil emulsion of P. granatum. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| congress 2.pdf | 1399/10/23 | 245429 | دانلود |
| certificate.jpg | 1399/10/23 | 164981 | دانلود |
