Evaluation of autonomic neuropathy in newly diagnosed and chronic type 2 diabetic patients: A retrospective cross-sectional study

Evaluation of autonomic neuropathy in newly diagnosed and chronic type 2 diabetic patients: A retrospective cross-sectional study


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نویسندگان: اکبر علی عسگرزاده , جلیل هوشیار قراملکی , فریبرز اکبرزاده , مهسا اسماعیل لو

کلمات کلیدی: Diabetes mellitus, Cardiovascular autonomic Disorder, Gastrointestinal autonomic disorder, Urinary tract autonomic dysfunction

نشریه: 56015 , 5 , 8 , 2020

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نویسنده ثبت کننده مقاله اکبر علی عسگرزاده
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات غدد درون ریز
کد مقاله 74687
عنوان فارسی مقاله Evaluation of autonomic neuropathy in newly diagnosed and chronic type 2 diabetic patients: A retrospective cross-sectional study
عنوان لاتین مقاله Evaluation of autonomic neuropathy in newly diagnosed and chronic type 2 diabetic patients: A retrospective cross-sectional study
ناشر 4
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق) Journal of Research in Clinical Medicine
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح دو – PubMed
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Introduction: Diabetic autonomic neuropathy is one of the most important complications of diabetes mellitus (DM) that ultimately occurs in most patients. The purpose of this study was to screen and diagnose latent cases of autonomic neuropathy among patients with a history of DM for over 10 years, and recently diagnosed diabetic patients. Methods: This cross-sectional study was performed on 104 patients, consisting of 52 type 2 DM (T2DM) patients diagnosed in the last 6 months; and 52 T2DM patients with a history of DM for more than 10 years) referred to outpatient endocrine clinic of Imam Reza Medical Center in Tabriz University of Medical Sciences between 2015-2016. Blood pressure, resting heart rate and corrected QT interval were evaluated according to standard methods. The history of gastrointestinal and urinary tract neuropathy was extracted from patients’ history and physical exam. Results: Of the 104 patients studied, 54 were male and 50 were female. Standing heart rate (P=0.02), resting (P<0.0002) and standing (P<0.0001) systolic blood pressure, and resting diastolic blood pressure (P=0.03) were significantly higher in chronic diabetic patients compared with newly diagnosed group. Additionally, blood glucose levels (P=0.03) and body mass index (BMI) (P<0.0001) were significantly higher in patients with neuropathy. Conclusion: Overall, the results of this study showed that in patients with T2DM, cardiac autonomic dysfunction is more common in patients with a longer history of DM.

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نویسنده نفر چندم مقاله
اکبر علی عسگرزادهدوم
جلیل هوشیار قراملکیسوم
فریبرز اکبرزادهچهارم
مهسا اسماعیل لواول

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