چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | سعید اصلان ابادی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده پزشکی |
| کد مقاله | 74681 |
| عنوان فارسی مقاله | بررسی حساسیت و اختصاصیت مارکر های بیوشیمیایی به روش ایمونوهیستو شیمیایی در تشخیص بیماری هیرشپرونگ |
| عنوان لاتین مقاله | EVALUATION THE SENSITIVITY AND SPECIFICITY OF BIOCHEMICAL MARKERS BY IMMUNOHISTOCHEMISTRY FOR DIAGNOSIS OF HIRSCHSPRUNG'S DISEASE |
| نوع ارائه | سخنرانی |
| عنوان کنگره / همایش | (Meeting of the International Pediatric Colorectal Club (PCC-2020 |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | India |
| شهر محل برگزاری کنگره/ همایش | New delhi |
| سال انتشار/ ارائه شمسی | 1399 |
| سال انتشار/ارائه میلادی | 2020 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1399/09/08 الی 1399/09/09 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://www.pcc2020.com/ |
| آدرس علمی (Affiliation) نویسنده متقاضی | Pediatric surgery department, Tabriz children hospital, Medicine faculty, Tabriz university of medical sciences |
| نویسنده | نفر چندم مقاله |
|---|---|
| سعید اصلان ابادی | اول |
| امیرحسین لادن | دوم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | EVALUATION THE SENSITIVITY AND SPECIFICITY OF BIOCHEMICAL MARKERS BY IMMUNOHISTOCHEMISTRY FOR DIAGNOSIS OF HIRSCHSPRUNG'S DISEASE SaeidAslanabadi, Amir Hossein Ladan Amir.h.Ladan@gmail.com (Islamic Republic of Iran) PURPOSE: According to importance of definite diagnosis of Hirschsprung's disease and burden of it on patient’s life and individual dependency on pathologists for histopathologic diagnosis, we wanted to evaluate some of introduced markers and their accuracy for this purpose. METHODS: During a two years period we involved 70 patients with probable diagnosis of Hirschsprung's disease in survey of examining Calretinin and Cajal cell markers ( CD34 , CD117 ) along with H&E pathologic evaluation for ganglion cells which is routine in our center . The final diagnosis was made through histopathologic results and clinical history of patients and again was confirmed by permanent pathologic evaluation after surgery. RESULTS: At last 33 patients went on definite surgery by diagnosis of Hirschsprung's disease according to clinical and pathologic criteria . In all 33 patients calretinin was negative and all excluded 37 patients has positive calretinin test . also wise Cajal cells all 70 patients were positive in identification of Cajal cells but there was obvious irregularity in aganglionic specimens . The specificity and sensivity for H&E was 100% and 94.59% accordingly. CONCLUSION: Using this markers specially calretinin can have the highest accuracy as gold standard of diagnosis as histopathologic evaluation. 11 |
| کلمات کلیدی | Hirschsprung's disease ; Calretinin ; Cajal cells ; Histopathology; CD34 ; CD117 |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Abstract Book latest.pdf | 1399/10/03 | 1090282 | دانلود |
| Dr Amir Hossein Ladan.pdf | 1399/10/03 | 396845 | دانلود |
