امکان جلو گیری از ایسکمی ری پرفیوژن و تاخیر فانکشن کلیه است؟چگونه؟

IS IT POSSIBLE TO PREVENT REPERFUSION ISCHEMIC INJURY AND DGF (DELAYED GRAFT FUNCTION) IN KIDNEY ALLOGRAFT? HOW?


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دانشگاه علوم پزشکی تبریز
دانشگاه علوم پزشکی تبریز

نویسندگان: افشار زمردی

عنوان کنگره / همایش: TTS2020 , Korea, South , کره جنوبی , 2020

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نویسنده ثبت کننده مقاله افشار زمردی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه دانشکده پزشکی
کد مقاله 74610
عنوان فارسی مقاله امکان جلو گیری از ایسکمی ری پرفیوژن و تاخیر فانکشن کلیه است؟چگونه؟
عنوان لاتین مقاله IS IT POSSIBLE TO PREVENT REPERFUSION ISCHEMIC INJURY AND DGF (DELAYED GRAFT FUNCTION) IN KIDNEY ALLOGRAFT? HOW?
نوع ارائه پوستر
عنوان کنگره / همایش TTS2020
نوع کنگره / همایش بین المللی
کشور محل برگزاری کنگره/ همایش Korea, South
شهر محل برگزاری کنگره/ همایش کره جنوبی
سال انتشار/ ارائه شمسی 1399
سال انتشار/ارائه میلادی 2020
تاریخ شمسی شروع و خاتمه کنگره/همایش 1399/06/22 الی 1399/06/25
آدرس لینک مقاله/ همایش در شبکه اینترنت Transplantation: September 2020 - Volume 104 - Issue S3 - p S391 doi: 10.1097/01.tp.0000700568.02344.59
آدرس علمی (Affiliation) نویسنده متقاضی Afshar zomorrodi professor of urology and head of organ transplant department and urology department Tabriz medical science university

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نویسنده نفر چندم مقاله
افشار زمردیاول

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عنوان متن
کلمات کلیدیdelayed function ,ischemic ,reperfusion
خلاصه مقالهIntroduction: Still, the kidney transplantation is the best choice for treatment of chronic renal failure, and if unrelated donor is option for transplantation deceased donor is the best modality for doing it, but there are many problems with deceased donor in which DGF is the most important one which sometimes may be result in graft lost or patient loss.so in our transplant department was decided to stopping or deferring DGF. Materials and Methods: In 20 Chronic renal failure patients age (between 25 and 55 years, 14 males, 6 females) 6 males and 4 females as donors were selected for kidney transplantation. In ten cadavers which in all of them the creatinine was high because of pre renal hyper azotemia. The minimum creatinine after improving the pre renal condition with fluid and rising blood pressure was 1.6mg/dl. In back table in every kidney through renal artery 80 mg papaverin injected and immediately after injection small bull dog applied. In all of them induction were with thymo and three medicines: prograft, prednisolone, celcept. Result: In all kidney after declamping immediately diuresis was started and at least in first 24 hours of transplantation the volume of urine was about 65500cc there was not any DGF case and at third day of surgery creatinine of serum was in normal range. Conclusion: Relaxing smoot muscle of artery by papaverine is the strongest prevention of DGF in which slowing blood flow and constriction in parenchyma of kidney is the first step for initiation DGF and up-regulated Toll like receptor in endothelial of artery it may change the fate of cadaveric kidney transplantation.

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