چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Int.J.Curr.Res.Aca.Rev.2015; 3(5):384-394384A B S T R A C TLung cancer is the main cause of mortalities resulted from cancer. After prostate cancer in men and breast cancer in women this malignancy is the most prevalent type of cancer among humans. Lung cancer is mostly diagnosed in its advanced stages and therefore its prognosis is often hard. The aforementioned studies stress the importance of expression of P63 in the tissue samples of different types of lung cancer. The aim of this research is to study the expression of P63 in the sputum samples of non-small cell lung cancerpatients. In a cross-sectional descriptive analytical study which was carried out in the pathology department of Tabriz University of Medical Sciences on patients with lung cancer, the expression of P63 in the sputum samples of patients with non-small cell lung cancerwas investigated. In this research, the expression of P63 in the sputum samples of 50 patients with non-small cell lung cancerand 50 healthy individuals was examined and compared. The mean age of non-small cell lung cancerpatients and members of the control group was 63.20 ± 15.01 and 62.04 ± 12.50 years, respectively (P=0.676). The mean expression of P63 in the non-small cell lung cancerpatients and control group participants was 32.40 ± 19.98 and 2.48 ± 4.09 percent, respectively. The mean expression of P63 in non-small cell lung cancerpatients was significantly higher than the control group (P<0.001). Mean of P63 expression in patients with lung SCC was 39.80 ± 19.39 percent, in patients with Adenocarcinoma was 25 ± 17.79 percent, in patients with Carcinoid atipic was 18 ± 12.54 percent and in patient with undifferentiated carcinoma was 60 percent. Mean expression of P63 was significantly higher in patients with lung SCC (P=0.010). Mean expression of P63 in patients with well differentiated tumor was significantly higher than patients with moderately differentiated tumor (P=0.018). |
| نویسنده | نفر چندم مقاله |
|---|---|
| اشرف فخرجو | اول |
| محمدرضا غفاری باویل | دوم |
| محمد میرزا آقازاده عطاری | سوم |
| زهره صناعت | چهارم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Ashraf Fakhrjou, et al.pdf | 1399/09/22 | 348643 | دانلود |
