DOES GRADE 3 ISCHEMIA ON ADMISSION ELECTROCARDIOGRAM PREDICT THE ST SEGMENT RESOLUTION FOLLOWING THROMBOLYSIS IN ST ELEVATION MYOCARDIAL INFARCTION?

DOES GRADE 3 ISCHEMIA ON ADMISSION ELECTROCARDIOGRAM PREDICT THE ST SEGMENT RESOLUTION FOLLOWING THROMBOLYSIS IN ST ELEVATION MYOCARDIAL INFARCTION?


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دانشگاه علوم پزشکی تبریز
دانشگاه علوم پزشکی تبریز

نویسندگان: صمد غفاری باویل , محمدرضا غفاری باویل

کلمات کلیدی: ST Elevation ̋Myocardial Infarction ̋ Grade 3 of Ischemia ̋ ST Resolution

نشریه: 42207 , 2 , 2 , 2009

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نویسنده ثبت کننده مقاله محمدرضا غفاری باویل
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات سل و بیماری های ریوی
کد مقاله 74531
عنوان فارسی مقاله DOES GRADE 3 ISCHEMIA ON ADMISSION ELECTROCARDIOGRAM PREDICT THE ST SEGMENT RESOLUTION FOLLOWING THROMBOLYSIS IN ST ELEVATION MYOCARDIAL INFARCTION?
عنوان لاتین مقاله DOES GRADE 3 ISCHEMIA ON ADMISSION ELECTROCARDIOGRAM PREDICT THE ST SEGMENT RESOLUTION FOLLOWING THROMBOLYSIS IN ST ELEVATION MYOCARDIAL INFARCTION?
ناشر 3
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق) JOURNAL OF CARDIOVASCULAR AND THORACIC RESEARCH
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Background: ST segment resolution (STR) following reperfusion therapy in STEMI patients has been shown to be a very strong predictor of outcome. Several studies investigated the strength of terminal QRS distortion (grade 3 ischemia) in predicting the failure of STR after reperfusion therapy. This study aimed to investigate whether grade 3 ischemia or other clinical characteristics could predict STR or not. Methods: In this cross-sectional study, we enrolled 100 consecutive acute STEMI patients who were admitted during 12 hours after the onset of their chest pain. Baseline clinical characteristics, electrocardiogram at 90 min, 3 hours, and 24 hours after the initiation of thrombolysis therapy, and echocardiographic data were retrived from the patients’ medical records. Results: The mean age of patients was 59±12 years old (13-93 years). Eighty percent were men and 46% were smoker. Thirty eight (38%) patients had grade 3 ischemia on their admission electrocardiogram. The frequency of grade 3 ischemia was different among patients with and without STR at 90 min (P=0.01), 3 hours (P=0.04), and 24 hours (P=0.04) after the thrombolytic therapy. But when comparing the outcome of patients with grade 2 and 3 ischemia on admission ECG, there was no significant difference in the frequency of complete STR between two groups in different time points. Only the frequency of failure to STR (STR<30%) was different among patients with grade 2 and 3 ischemia, 24 hours after thrombolysis (P=0.03). Odds ratio for grade 3 ischemia in predicting failure to STR was 1.80 (with 95% CI: 0.6-5.2). Conclusions: The presence of grade 3 ischemia on admission electrocardiogram was predictor of incomplete STR at 90 min, 3 h and 24 h after the initiation of thrombolysis and was associated with higher rates of coronary angiography and angioplasty.

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نویسنده نفر چندم مقاله
صمد غفاری باویلاول
محمدرضا غفاری باویلدوم

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