Treatment of erythrasma: A double-blinded randomized controlled trial on the clinical application of clotrimazole and sertaconazole

Treatment of erythrasma: A double-blinded randomized controlled trial on the clinical application of clotrimazole and sertaconazole


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دانشگاه علوم پزشکی تبریز
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نویسندگان: حمیده هریزچی قدیم , آیدا سلمان مهاجر , سیدمحمدسالار حسینی

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نشریه: 56015 , پیوسته , 8 , 2020

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نویسنده ثبت کننده مقاله سیدمحمدسالار حسینی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه کمیته تحقیقات دانشجویی
کد مقاله 74400
عنوان فارسی مقاله Treatment of erythrasma: A double-blinded randomized controlled trial on the clinical application of clotrimazole and sertaconazole
عنوان لاتین مقاله Treatment of erythrasma: A double-blinded randomized controlled trial on the clinical application of clotrimazole and sertaconazole
ناشر 4
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح چهار – Index Copernicus
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Introduction: Topical clotrimazole and sertaconazole may be effective in the treatment of erythrasma, a superficial skin infection developed by a group of aerobic microorganisms. This study aimed to compare the effect of clotrimazole and sertaconazole on erythrasma. Methods: In this double-blinded randomized controlled trial, 40 age-matched patients with confirmed erythrasma diagnosis were divided into two equal groups; one treated with topical 2% sertaconazole and the other with topical 1% clotrimazole. The clinical features of erythrasma were monitored for two weeks (baseline, day 7, and day 14) and compared. Data were analyzed using SPSS v16 software. Results: On day 7, in clotrimazole group, reduction in erythema and pigmentation were more prominent in comparison to the sertaconazole group (P = 0.02 and P = 0.005, respectively), but there was no difference considering scaling reduction between groups. On day 14, in terms of erythema reduction, the clotrimazole group performed better compared to the sertaconazole group (P = 0.04). Both groups had a significant reduction in erythrasma symptoms during their treatment period (P < 0.001). Conclusions: Regarding the results, both clotrimazole and sertaconazole are effective medications for erythrasma treatment. Still, clotrimazole has a faster recovery process in comparison to sertaconazole, but no significant difference is observed in outcomes after two weeks of treatment.

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نویسنده نفر چندم مقاله
حمیده هریزچی قدیماول
آیدا سلمان مهاجرسوم
سیدمحمدسالار حسینیچهارم

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