Curcumin-loaded hayaluronic acid nanohydrogels as promising scaffolds for odontogenic differentiation of dental pulp stem cells

Curcumin-loaded hayaluronic acid nanohydrogels as promising scaffolds for odontogenic differentiation of dental pulp stem cells


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اطلاعات تفضیلی
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نویسندگان: الهام احمدیان

عنوان کنگره / همایش: OpenTox Virtual Conference 2020 Program , Switzerland , Zeiningen , 2020

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نویسنده ثبت کننده مقاله الهام احمدیان
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات کلیه
کد مقاله 74392
عنوان فارسی مقاله Curcumin-loaded hayaluronic acid nanohydrogels as promising scaffolds for odontogenic differentiation of dental pulp stem cells
عنوان لاتین مقاله Curcumin-loaded hayaluronic acid nanohydrogels as promising scaffolds for odontogenic differentiation of dental pulp stem cells
نوع ارائه پوستر
عنوان کنگره / همایش OpenTox Virtual Conference 2020 Program
نوع کنگره / همایش بین المللی
کشور محل برگزاری کنگره/ همایش Switzerland
شهر محل برگزاری کنگره/ همایش Zeiningen
سال انتشار/ ارائه شمسی 1399
سال انتشار/ارائه میلادی 2020
تاریخ شمسی شروع و خاتمه کنگره/همایش 1399/06/31 الی 1399/07/04
آدرس لینک مقاله/ همایش در شبکه اینترنت OpenTox Virtual Conference 2020 Program | OpenTox
آدرس علمی (Affiliation) نویسنده متقاضی Kidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

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الهام احمدیاناول

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کلمات کلیدیstem cell, Curcumin, hayaluronic acid, nanohydrogels
خلاصه مقاله..Introduction: Periodontitis can result in progressive damage of periodontal tissues which support the tooth. Developing novel biomaterials in dental regeneration has markedly enhanced the current treatment opportunities. The present investigation evaluated the curcumin loaded hyaluronic acid hydrogels as promising scaffolds for odontogenic tissue engineering. Methods: The scaffolds were prepared through anti solvent method, and then the physicochemical specification and the cytotoxic effects and differentiation of dental pulp stem cells were determined. Results: The nano-scaffolds were successfully synthetized with a mono-dispersed nano scale diameter (290.10 nm), negative surface charge and uniform network-shaped morphology. Human dental pulp stem cells were harvested on the developed nanoscafolds. Nanoscafolds exhibited a significant proliferative effect and induced the differentiation of the stem cells. Conclusion: The incorporation of different compounds to nano-scaffolds such as curcumin not only increases the physiochemical properties of scaffolds in stem cell proliferation and differentiation but also might exert anti-bacterial and anti-inflammatory effects

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2020 OpenTox Euro-Cert_Elham Ahmadian.pdf1399/08/18454566دانلود
opentox.pdf1399/08/18262069دانلود