| Ginger is a medicinal plant with antioxidant, anti-bacterial, anti-inflammatory and anti-fungal properties. The shape of effervescent tablet
is a new form of this product for use as a mouthwash. This study investigated the cytotoxicity and antimicrobial properties of gingerly
effervescent tablets under laboratory conditions. In this study, MTT assay was done to evaluate in-vitro gingival fibroblast cytotoxicity
during 24, 48 and 72 hours. In addition, the effect of antimicrobial properties on common bacterial and oral fungi was investigated. Pvalue was considered significantly less than 0.05. There was no significant difference between the mean of live cells in groups with 24,
48 and 72 duration (P-value = 0.071). There was no significant difference between ginger group and control group (P<0.05). Minimum
inhibitory concentration (MIC) of effervescent tablet was different, ranging from 10 mg/ml for Candidas family to 20 mg/ml for
Staphylococcus and 40 mg/ml for negative grams. According to the results, it can be concluded that gingerly effervescent tablets have no
toxic effect after 72 hours of exposureto gingival fibroblasts. Its suitable antimicrobial properties for fungi makes it useful for the control
of infection and as an ideal mouthwash. |