Diagnostic value of chest CT in Iranian patients with suspected COVID-19
Diagnostic value of chest CT in Iranian patients with suspected COVID-19
نویسندگان: هانیه صالحی پورمهر , حجت پورفتحی نعمت آباد , محمد کاظم طرزمنی , مرتضی قوجازاده , بهروز نقیلی حکم آبادی , آرمین زرین تن , سکینه حاج ابراهیمی , رضا مهدی پور
کلمات کلیدی: Sensitivity, Specificity, Chest CT, RT-PCR, COVID-19
نشریه: 6255 , 0 , 11 , 2020
| نویسنده ثبت کننده مقاله |
سکینه حاج ابراهیمی |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات پزشکی مبتنی بر شواهد EBM |
| کد مقاله |
74290 |
| عنوان فارسی مقاله |
Diagnostic value of chest CT in Iranian patients with suspected COVID-19 |
| عنوان لاتین مقاله |
Diagnostic value of chest CT in Iranian patients with suspected COVID-19 |
| ناشر |
8 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
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| Background: In the current COVID-19 pandemic, there is a rising need for a rapid and reliable diagnostic tool. We hypothesized that chest computed tomography (CT) can be a potential alternative for reverse transcription-polymerase chain reaction (RT-PCR).
The aim of this study was to compare the diagnostic value of chest CT and RT-PCR in Iranian patients with suspected COVID-19.
Methods: In a retrospective, single-center case series, 568 consecutive hospitalized or outpatient patients with suspected COVID-19 underwent chest CT and/or RT-PCR testing at Imam Reza Hospital, the tertiary teaching hospital of Tabriz University of Medical Sciences in Iran, from February 21 and March 28, 2020.
Results: The sensitivity of chest CT for signifying COVID-19 was 64% (95% CI: 56%–71%) on the basis of positive RT-PCR results as a standard method. CT imaging also had a specificity of 77% (95% CI: 73%–81%), positive predictive value of 35% (95% CI: 0.31–0.39), negative predictive value of 66% (95% CI: 0.61–0.69), positive likelihood ratio of 2.79 (95% CI: 2.26–3.46), and negative likelihood ratio of 0.47 (95% CI: 0.38–0.57).
Conclusion: Chest CT had higher specificity than RT-PCR in the diagnosis of COVID-19, . Therefore, it can play a crucial role in the early diagnosis. Similar to the previous studies, the typical CT features were patchy ground-glass opacities as well as peripheral aspects of the lungs consolidations. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| CT-article.pdf | 1399/08/13 | 1321396 | دانلود |