| In this work, a series of oxidized starch-based bio-nanocomposites (OS/CuO) were prepared and
investigated as colon drug delivery vehicles. The appearance of peaks at 400–800 cm1 of FTIR
spectrum, as well as, peaks at 2h 35, 39, and 49 of XRD spectrum could be a good sign for successful synthesis of the CuO within hydrogel network. The effect of Cu2þ concentration on swelling, NPX loading, and release behavior was examined and the highest value obtained for the C2
sample. Moreover, C4 displayed the highest antibacterial activity. Obtained results indicated that
the prepared systems are suitable for use in medical applications. |