چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| بهروز نقیلی حکم آبادی | چهارم |
| لیلا رهبرنیا | دوم |
| علیرضا دهناد | سوم |
| عنوان | متن |
|---|---|
| کلمات کلیدی | Acinetobacter baumannii, antibiotics resistance,carbapenemase |
| خلاصه مقاله | Background Escalating prevalence of of carbapenem-resistance (CR) and multi-drug resistance (MDR) in A. baumannii has limited the antibiotic therapy of related infections. This study was conducted to determine the prevalence of carbapenemases among the A. baumannii clinical isolates. Methods A cross-sectional study was conducted in Tabriz, North-west Iran. A total of 128 A. baumannii isolates were collected from Imam Reza and Sina hospitals of Tabriz city. Isolates were identified by standard biochemical tests and molecular detection of bla OXA-51 gene. Antimicrobial susceptibility profile was examined via the disk diffusion method. Polymerase chain reaction (PCR) and sequencing were performed to detect blaOXA-23, blaOXA-143 and blaOXA-58 genes among carbapenem resistant A. baumannii isolates. Results: All of 128 clinical isolates were carrying blaOXA-51 gene, 98% of the isolates were resistant to imipenem and 100% resistant to meropenem. Based on PCR results, 64% of the carbapenem resistant isolates were carrying blaOXA-23 and 42% of the isolates were positive for blaOXA-143 gene and none of them had the bla OXA-58 gene. Conclusion: Our results are indicating high incidence of the bla OXA-23 like genes and the prevalence of blaOXA-143 gene among the carbapenem resistant A. baumannii strains in our study region. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| abstract.jpg | 1399/07/21 | 64455 | دانلود |
| certificate.jpg | 1399/07/21 | 175156 | دانلود |
| congress certificate.pdf | 1399/07/29 | 267400 | دانلود |
