Effects of caffeine supplementation on oxidative stress, exercise-induced muscle damage and leukocytosis

Effects of caffeine supplementation on oxidative stress, exercise-induced muscle damage and leukocytosis


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نویسندگان: رضا مهدوی , عزیز همایونی راد , افشار جعفری

کلمات کلیدی: Caffeine, Muscular damage, Oxidative stress, Wingate-test

نشریه: 55429 , 3 , 18 , 2012

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نویسنده ثبت کننده مقاله رضا مهدوی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات علوم تغذیه
کد مقاله 74013
عنوان فارسی مقاله Effects of caffeine supplementation on oxidative stress, exercise-induced muscle damage and leukocytosis
عنوان لاتین مقاله Effects of caffeine supplementation on oxidative stress, exercise-induced muscle damage and leukocytosis
ناشر 4
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Athletes use variety of ergogenic aids such as caffeine to improve their performance. Many factors such as oxidative stress, muscular-damage and decreased immune function may have negative effect on athletic performance. However effects of caffeine on mentioned factors in female athletes after supramaximal exercise are rare and obscure. Methods: In this double-blind, cross-over study, 26 female basketball players supplemented with 5mg.kg-1 caffeine or dextrose as a placebo followed by Wingate test. Blood samples were obtained before and 5 minutes post-exercise for determining the serum malondialdehyde (MDA), total antioxidant capacity (TAC), creatine kinase (CK) activity and blood’s white blood cells (WBC). Kolmogrov-smirnov statistic test and paired t-test were used to analyze data. Results: After the Wingate test, WBC, lymphocyte, granulocyte count and serum MDA levels, were increased significantly in both groups(P<0.001). No significant differences were observed in increased levels between caffeine supplemented and placebo groups(P>0.05). Furthermore the changes in CK activity and TAC levels were not statistically significant in any of the groups (P>0.05). Conclusion: The findings indicated that 5mg.kg-1 caffeine supplementation did not have significant adverse effect on oxidative stress, exercise-induced muscle damage and leukocytosis after Wingate test.

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نویسنده نفر چندم مقاله
رضا مهدویاول
عزیز همایونی رادسوم
افشار جعفریچهارم

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PHARM-18-177.pdf1399/07/18450990دانلود