چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Objective This research was done amid at investigating the synbiotic supplement influences on serum glycemic indexes, lipids as well as apelin rates and obesity values in PCOS patients. Materials and methods A total of 68 obese or overweight patients (20-44 years old) with PCOS were participated to conduct a randomized double-blinded placebo controlled clinical trial. A total of 34 people in the synbiotic group and also 34 people in the placebo group received a synbiotic supplement or placebo daily throughout 8 weeks. Fasting blood specimens, anthropometric measurements and dietary intake data were gathered at the outset and at the finale of the study. The information was analyzed by independent t-test, paired t-test and analysis of covariance and chi-square test. Results Synbiotic supplementation significantly decreased serum fasting glucose (p=0.02), insulin (p=0.001), homeostatic model assessment for insulin resistance (p=0.001), weight (p=0.02), body mass index (p=0.02), waist circumference (p=0.01), hip circumference (p=0.02), waist to height ratio (p=0.02) and significantly increased high-density lipoprotein cholesterol (p=0.02) compared to placebo. At the end of the trial, no significant changes were seen in serum total cholesterol, triglyceride, low-density lipoprotein cholesterol, and apelin levels as well as waist to hip ratio between two groups. Conclusion Synbiotic supplementation improved glycemic indexes, lipid profile and obesity values in women with PCOS. These beneficial effects were not related with alteration in serum apelin levels( Registration number: IRCT20100408003664N19). |
| نویسنده | نفر چندم مقاله |
|---|---|
| سیما درویشی | اول |
| مریم رف رف | دوم |
| محمد اصغری جعفرآبادی | سوم |
| لعیا فرزدی | چهارم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| certificate-file.pdf | 1399/07/30 | 296842 | دانلود |
| dar2.docx | 1399/07/16 | 15387 | دانلود |
