The mechanisms involved in obesity-induced male infertility
The mechanisms involved in obesity-induced male infertility
نویسندگان: حامد حیدری , فریبا قیاسی , صابر قادرپور , رعنا کیهان منش
کلمات کلیدی: Obesity, inflammation, oxidative stress, male fertility, spermatogenesis
نشریه: 8670 , 9 , 16 , 2020
| نویسنده ثبت کننده مقاله |
رعنا کیهان منش |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات کاربردی دارویی |
| کد مقاله |
73909 |
| عنوان فارسی مقاله |
The mechanisms involved in obesity-induced male infertility |
| عنوان لاتین مقاله |
The mechanisms involved in obesity-induced male infertility |
| ناشر |
4 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Review Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Abstract: Background: Obesity resulted by imbalance between the intake of energy and energy
consumption can lead to growth and metabolic disease development in people. Both in obese men
and animal models, several studies indicate that obesity leads to male infertility.
Objective: This review has discussed some mechanisms involved in obesity-induced male infertility.
Method: Online documents were searched through Science Direct, Pubmed, Scopus, and Google
Scholar websites dating from 1959 to recognize studies on obesity, kisspeptin, leptin, and infertility.
Results: Obesity induced elevated inflammatory cytokines and oxidative stress can affect male reproductive
functions, including spermatogenesis disorders, reduced male fertility power and hormones
involved in the hypothalamus-pituitary-gonadal axis.
Conclusion: There is significant evidence that obesity resulted in male infertility. Obesity has a
negative effect on male reproductive function via several mechanisms such as inflammation and
oxidative stress. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
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