Morphine and its metabolites: Review and update on analytical methodologies in the biological samples
Morphine and its metabolites: Review and update on analytical methodologies in the biological samples
نویسندگان: رقیه امینی , الهه رحیم پور , ابوالقاسم جویبان
کلمات کلیدی: Morphine and its metabolites, Biological samples, Analytical determination,
Opioid, Drugs of abuse
نشریه: 4464 , 16 , 12 , 2020
| نویسنده ثبت کننده مقاله |
ابوالقاسم جویبان |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات آنالیز دارویی |
| کد مقاله |
73891 |
| عنوان فارسی مقاله |
Morphine and its metabolites: Review and update on analytical methodologies in the biological samples |
| عنوان لاتین مقاله |
Morphine and its metabolites: Review and update on analytical methodologies in the biological samples |
| ناشر |
3 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Review Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Morphine (MO), as an opioid analgesic is used for treatment of the moderate to severe pains
particularly the cancer-related pains. Pharmacologic studies on MO are complicated due to
drug binding to the protein or metabolization to active metabolites, and even inter-individual
variability. This necessitates the selection of a reliable analytical method for monitoring MO
and the concentrations of its metabolites in the biological samples for the pharmacokinetic or
pharmacodynamic investigations. Therefore this study was conducted to review all the
analytical researches carried out on MO and its metabolites in the biological samples during
2007 − 2019 as an update to the study by Bosch et al. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| Bioanalysis 2020 in press.pdf | 1399/07/14 | 840508 | دانلود |