چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| The solubility of lamotrigine (LTG) was reported in full concentration range of acetonitrile + water at T = 293.15–313.15 K. The solubility data were correlated by the Jouyban-Acree, Jouyban-Acree-van’t Hoff, NRTL, UNIQUAC and Wilson equations in addition to modified Wilson and Machatha. With respect to the obtained %ARDs, Jouyban-Acree is superior to Jouyban-Acree-van’t Hoff and the order of %ARDs for non-linear models is NRTL < UNIQUAC < Wilson. Moreover, the Machatha non-linear is more consistent with experimental data rather than modified Wilson for correlating the data with regard to the solvent composition. Finally, apparent standard Gibbs energy, enthalpy and entropy of dissolution and mixing, ΔG∘soln, ΔH∘soln, ΔS∘soln, ΔG∘mix, ΔH∘mix, ΔS∘mix of LTG in aqueous mixtures of acetonitrile were computed at mean harmonic temperature Thm = 303.0 K. The positive variable of ΔG∘soln suggesting the favourability of dissolution in acetonitrile-rich mixtures and ‘entropy-driven’ nature of it in only four cases. |
| نویسنده | نفر چندم مقاله |
|---|---|
| سیده نرجس میرحیدری | اول |
| محمد برزگر جلالی | دوم |
| ابوالقاسم جویبان | چهارم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Phys Chem Liq in press doi 10-1080-00319104-2019-1636380.pdf | 1399/07/13 | 1677922 | دانلود |
