چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Temperature-dependent solubility data for mesalazine in the binary system of polyethylene glycol 400 (PEG 400)/water are determined by a shake-flask method at 293.2–313.2 K. The solubility data are validated to five different computational models including the van't Hoff, the mixture response surface, the Yalkowsky, the Jouyban-Acree, and the Jouyban-Acree-van't Hoff. All the investigated models have good correlation and validation according to obtained the mean relative deviations (MRD%) for back-calculated data. Moreover, apparent thermodynamic analysis shows an endothermic process for mesalazine in (PEG 400+water) mixtures. Further, based on inverse Kirkwood-Buff integrals is observed that mesalazine is preferentially solvated by PEG in all the mixtures. |
| نویسنده | نفر چندم مقاله |
|---|---|
| میلاد مرادی | اول |
| الهه رحیم پور | دوم |
| سالار همتی | سوم |
| محمد برزگر جلالی | پنجم |
| ابوالقاسم جویبان | ششم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| J Mol Liq 314 (2020) 113546.pdf | 1399/07/12 | 683912 | دانلود |
