Does resveratrol affect prepared sperm parameters and chromatin quality in normozoospermic and asthenozoospermic patients before and after freezing? A lab trial study
Does resveratrol affect prepared sperm parameters and chromatin quality in normozoospermic and asthenozoospermic patients before and after freezing? A lab trial study
نویسندگان: حامد همیشه کار
کلمات کلیدی: Resveratrol, Chromatin, Motility, Spermatozoa, Freeze.
نشریه: 0 , 9 , 18 , 2020
| نویسنده ثبت کننده مقاله |
حامد همیشه کار |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات کاربردی دارویی |
| کد مقاله |
73710 |
| عنوان فارسی مقاله |
Does resveratrol affect prepared sperm parameters and chromatin quality in normozoospermic and asthenozoospermic patients before and after freezing? A lab trial study |
| عنوان لاتین مقاله |
Does resveratrol affect prepared sperm parameters and chromatin quality in normozoospermic and asthenozoospermic patients before and after freezing? A lab trial study |
| ناشر |
9 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
International Journal of Reproductive BioMedicine |
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Background: Previous studies have examined the effect of resveratrol as a potent
antioxidant for free radicals in semen. While, the prepared spermatozoa are more
affected by ROS factors due to centrifugation and incubation.
Objective: To evaluate the RSV’s effects on the prepared sperm parameters and
chromatin quality in both normozoospermic and asthenozoospermic cases before and
after freezing.
Materials and Methods: The sample of 10 normozoospermic and asthenozoospermic
men was prepared through the swim-up method. The groups were then divided into
two samples of control and experimental (exposure to 30 µmol/l of RSV) to evaluate
and compare the sperm parameters and chromatin quality before and after freezing.
Results: The motility and viability of spermatozoa were seen to be significantly different
before and after freezing separately in the control and treatment samples of the groups
(p ≤ 0.001 and p = 0.001, respectively). However, the stated difference between the
control and treatment samples of normozoospermic and asthenozoospermic patients
were not significant (p > 0.05). In addition, the sperm morphology and chromatin quality
were not significantly different between the two samples of each group; nonetheless,
chromatin quality of the treated sample was better than that of the control before and
after freezing.
Conclusion: Despite the protective effects of RSV on the semen samples, RSV
cannot affect significantly the prepared sperms parameters and chromatin quality in
normozoospermic and asthenozoospermic patients. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| ijrm-v18n9p755-en.pdf | 1399/07/08 | 658164 | دانلود |