چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| We appreciate the interest in our article and thank Dr. Beuy Joob for his knowledgeable comments on our study. Non-coding variants (rs17782313) of the MC4R have been related to susceptibility to polygenic obesity [1]. Therefore, we agree that additional SNPs within the MC4R gene, also SNPs in other genes implicated in the pathogenesis of obesity and cardio-metabolic factors, may be involved, and these should be considered and assessed in further studies. However, our study provides valuable information, as a hypothesis, or be evaluated by cohort studies [2, 3]. Moreover, we agree that other lifestyle and environmental factors could affect our observed results and as well as, the confounding role of other unknown factors is undeniable. Further studies should mostly focus on the effect of polygenic interactions between obesity and its metabolic risk factors. |
| نویسنده | نفر چندم مقاله |
|---|---|
| مهدیه عباسعلیزاد فرهنگی | اول |
| محدثه محمدی | سوم |
| مهدیه خدارحمی | اول |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 2020-277.pdf | 1399/07/05 | 439964 | دانلود |
