A 14-year-old female with fever, rash, lymphadenopathy, and pancytopenia: a case report
A 14-year-old female with fever, rash, lymphadenopathy, and pancytopenia: a case report
نویسندگان: مجتبی ورشوچی فرد , ریحانه روانبخش گاوگانی , فاطمه روانبخش گاوگانی , بهروز نقیلی حکم آبادی , ژینوس بیات ماکو , پریناز پورشاهوردی
کلمات کلیدی: Keywords: Fever, Rash, Lymphadenopathy, Pancytopenia
نشریه: 20750 , 1 , 14 , 2020
| نویسنده ثبت کننده مقاله |
فاطمه روانبخش گاوگانی |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
دانشکده پزشکی |
| کد مقاله |
73587 |
| عنوان فارسی مقاله |
A 14-year-old female with fever, rash, lymphadenopathy, and pancytopenia: a case report |
| عنوان لاتین مقاله |
A 14-year-old female with fever, rash, lymphadenopathy, and pancytopenia: a case report |
| ناشر |
6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Case Report |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح دو – PubMed |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Abstract
Background: Anticonvulsant hypersensitivity syndrome is a rare adverse drug reaction associated with aromatic
anticonvulsant drugs. This syndrome can range from mild cutaneous rash to drug reaction with eosinophilia and
systemic symptoms that include fever, rash, lymphadenopathy, pancytopenia, and involvement of multiple internal
organs. We aimed to report this case in the literature and make physicians aware of the uncommon symptoms of
this syndrome when they prescribe antiepileptic medications in particular.
Case presentation: A 14-year-old Middle Eastern female patient from Iran with free past medical and allergic
history was admitted to hospital because of fever, rash, lymphadenopathy, and pancytopenia after taking
anticonvulsants due to new-onset seizure. High fever and cutaneous rash along with lymphadenopathy following
administration of anticonvulsant medications that could not be explained by other causes alerted the physician to the
possibility of this syndrome. Our investigation revealed no further diagnosis and 1 week after discontinuation of the drugs,
her symptoms were resolved. Anticonvulsant hypersensitivity syndrome is a diagnosis of exclusion and immediate
discontinuation of the suspicious drugs is necessary. Hence, early recognition can prevent permanent multiorgan damage.
Conclusions: Chlorpheniramine as a simple treatment was provided for this syndrome. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| a 14 year old female.pdf | 1399/07/01 | 510496 | دانلود |