| Objectives: We aim to measure dietary infammatory index (DII) and its association with functional status, pain intensity and quality of life (QOL) in patients with knee osteoarthritis (KOA). Dietary information from 220 qualifed patients
with KOA was collected by a 168-item food frequency questionnaire. The functional status, pain intensity and QOL
were evaluated by Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire, Visual
Analogue Scale (VAS) and SF36 questionnaire respectively.
Results: Linear regression analysis showed that the DII was signifcantly associated with VAS (p=0.040; β=0.151),
and physical function (p=0.039; β=−0.184), emotional wellbeing (p=0.048; β=−0.158) and pain (p=0.020;
β=0.161) scales and physical health (p=0.047; β=0.110) subscale of QOL after adjusting for age, sex, body mass
index, and physical activity. There was no signifcant diferences concerning WOMAC across the DII tertiles with and
without adjustment to probable confounders (Ptrend=0.091 and 0.181, respectively). After adjustment, a signifcantly
increased severe pain odds was observed in the highest tertile of DII score in comparison with the lowest tertile (OR
tertile 3 vs. 1=1.55, 95% CI 1.04–2.31; Ptrend=0.04). |