چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| MicroRNAs (miRNAs) characterized by small, noncoding RNAs have a fundamental role in the regulation of gene expression at the post‐transcriptional level. Additionally, miRNAs have recently been identified as potential regulators of various genes involved in the pathogenesis of the autoimmune and inflammatory disease. So far, the interaction between miRNAs and T lymphocytes in the immune response as a new and significant topic has not been emphasized substantially. The role of miRNAs in different biological processes including apoptosis, immune checkpoints and the activation of immune cells is still unclear. Aberrant miRNA expression profile affects various aspects of T‐cell function. Accordingly, in this literature review, we summarized the role of significant miRNAs in T‐cell development processes. Consequently, we demonstrated precise mechanisms that candidate miRNAs interfere in Immune response mediated by different types of T cells. We believe that a good understanding of the interaction between miRNAs and immune response contributes to the new therapeutic strategies in relation to disease with an immunological origin. |
| نویسنده | نفر چندم مقاله |
|---|---|
| بهنام امام قلی زاده | اول |
| بشیر مسیبی | دوم |
| هانیه بیرامپور | چهارم |
| محمدرضا علی وند | ششم |
| پرویز حسن پور | هفتم |
| سعید سلالی | هشتم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| microRNAs involved.pdf | 1399/06/19 | 1624290 | دانلود |
