Evaluation of stroke related risk factors in wake up and non-wake up stroke patients

Evaluation of stroke related risk factors in wake up and non-wake up stroke patients


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نویسندگان: الیار صادقی حکم آبادی , صمد شمس وحدتی , رضا ریخته گر غیاثی , آیسا رضابخش

کلمات کلیدی: Wake Up Stroke; Risk Factors; Familiar History; Hematologic Characteristics

نشریه: 0 , 2 , 16 , 2020

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نویسنده ثبت کننده مقاله صمد شمس وحدتی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه تیم های تحقیقاتی دانشگاه
کد مقاله 73439
عنوان فارسی مقاله Evaluation of stroke related risk factors in wake up and non-wake up stroke patients
عنوان لاتین مقاله Evaluation of stroke related risk factors in wake up and non-wake up stroke patients
ناشر 5
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Wake-Up Stroke (WUS) is defined as a stroke with the unclear onset of symptoms and subsequent neurological deficits which perceived upon awakening. WUS patients are often excluded from acute fibrinolytic and reperfusion therapy due to the unknown exact time of symptoms onset. This study aimed to evaluate patients with and without WUS characteristics and associated risk factors at two tertiary hospitals. First, we prospectively evaluated consecutive patients with stroke symptoms and determined stroke sub groups by using Computed Tomography (CT) scan. Next, demographic and clinical characteristics including past medical and drug consumption history as well as cardiac function index (ejection fraction), LDL (mg/dl) level and hematologic parameters: hemoglobin (Hb); hematocrit (Hct); platelet (Plt) were assessed. Results: 510 patients (56.1% men and 43.9% women) with averaged age of 70 and 72 years were studied, respectively. Of 510 patients, 405 (79.4%) had non-WUS stroke (known-onset stroke) and 105 (20.6%) had WUS strokes (unknown-onset stroke). The WUS occurrence most likely was observed in ischemic stroke compared to hemorrhagic one. No significant differences were found between patients from both groups regarding stroke risk factors. However, hypertension and family history were more common in patients with WUS (p>0.05). Moreover, individuals with a previous cerebrovascular accident in WUS group were almost similar to non-WUS counterparts. No differences also detected in case of hematologic characteristics, heart function index and LDL levels between study groups (p>0.05). Together, wake-up stroke occurs in approximately 20% of stroke subjects. In this study, patients with WUS had more hypertension and family history.

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نویسنده نفر چندم مقاله
الیار صادقی حکم آبادیاول
صمد شمس وحدتیدوم
رضا ریخته گر غیاثیسوم
آیسا رضابخشپنجم

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