چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Objective This study assessed the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), mean platelet volume, platelet distribution width, and red cell distribution width (RDW) in systemic lupus erythematosus (SLE) patients and their correlation with disease activity. Methods Two hundred eight SLE patients and 205 age- and sex-matched healthy controls were included. Disease activity was assessed using the systemic lupus erythematosus disease activity index 2000, and hematological indices were determined. Results Lymphocyte and platelet counts were significantly lower in SLE patients than in the controls, while the NLR, PLR, and RDW were significantly higher (P < .05). In patients with active disease, the neutrophil counts, NLR, and PLR were significantly higher than in those with inactive disease (P < .05), while the lymphocyte count was significantly lower (P < .05). Based on receiver operating characteristic curve analyses, only for lymphocyte count and PLR. The area under curve was significantly higher (P = .001 and P = .053, respectively). Conclusion PLR can serve as a biomarker for indicating SLE disease activity. |
| نویسنده | نفر چندم مقاله |
|---|---|
| امیرحسین پیروی | اول |
| آیدا مالک مهدوی | اول |
| علیرضا خبازی اسکویی | دوم |
| مهرزاد حاج علیلوی بناب | سوم |
| ابراهیم سخی نیا | چهارم |
| نادره رشتچی زاده | پنجم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Clinical Usefulness of Hematologic Indices as Predictive Parameters for Systemic Lupus Erythematosus .pdf | 1399/06/14 | 298186 | دانلود |
