چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Long-term exposure to stressful conditions is associated with neurochemical changes in the cerebral structures, which ultimately result in mood disorders including, but not limited to, depression and anxiety. Finding an effective way to deal with these conditions has always been of interest to researchers. The goal of this review was to discuss the biochemical pathways and mechanisms restraint/immobilization stress induces depression and anxiety disorders, focusing mainly on oxidative damage and neuroinflammation in the central nervous system (CNS), to gain a better understanding of the mechanisms and possible prevention and treatment. Evidence confirms that stress generates high levels of free radicals and reactive oxygen/nitrogen species and neuroinflammation in the brain regions implicated in the pathophysiology of depression and anxiety. |
| نویسنده | نفر چندم مقاله |
|---|---|
| کیارش فکری | اول |
| علیرضا محجل نائبی | دوم |
| سعید صدیق اعتقاد | سوم |
| فرشته فرج دخت | چهارم |
| جواد محمودی | پنجم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 10.1134@s181971242002004x.pdf | 1399/06/01 | 1194237 | دانلود |
