چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| هانیه صالحی پورمهر | اول |
| سکینه حاج ابراهیمی | دوم |
| ندا اسعدی شالی | سوم |
| فریبا پاشازاده | چهارم |
| عنوان | متن |
|---|---|
| کلمات کلیدی | |
| خلاصه مقاله | Aim:Misconduct is one of the important issues on research integrity. Cochrane systematic reviews are known for their best level of evidences. Considering kidney and transplant group is responsible for identifying all trial-related kidney disease, evaluation the relevance and quality of trials, collection and analysis of trial data and preparing reports for inclusion them in systematic reviews of the Cochrane Database and regarding kidney disease is the 9th leading cause of death in the United State, hence this study aimed to assess quality of randomized controlled trials included in Cochrane systematic reviews of kidney and transplant group. Methods:This analytic cross-sectional study was conducted on 147 systematic reviews of kidney and transplant group of Cochrane reviews and a total of 2475 RCTs had been appraised by CONSORT checklist that included all kinds of biases (selection, performance, detection, attrition and reporting. Descriptive statistics were used to analysis the data through SPSS 16 and also partial correlation was done to report the outcomes. Results:In a total of 2457 RCTs the most high risk bias had been seen in Random Sequence Generation bias (55%) and Performance bias (35%) respectively. Whereas 20% of studies in allocation bias, 41% incomplete outcome bias, 46% selection bias and 33% detection bias were low risk. According to the findings, during 2008-2009, high random sequence generation bias dramatically has increased and after decreasing, gradual growth has been continuing over the time. Furthermore, low detection bias has reduced surprisingly in 2011 then decreased during 20122013. Conclusion:Regarding to high risks of performance and random sequence generation biases in understudied RCTs, it’s obvious they have critical structure deficiencies. Therefore, it’s recommended observing integrity principles for preventing research misconduct. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 12.pdf | 1399/05/31 | 282494 | دانلود |
| 12-1.pdf | 1399/05/31 | 5084566 | دانلود |
