| نویسنده ثبت کننده مقاله | مهین آهنگر اسکوئی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده پزشکی |
| کد مقاله | 73257 |
| عنوان فارسی مقاله | عدم وجود سایتومگالوویروس در سرطان پستان زنان در تبریز |
| عنوان لاتین مقاله | Absence of Cytomegalovirus in Women with breast cancer in Tabriz |
| نوع ارائه | پوستر |
| عنوان کنگره / همایش | بیست و یکمین کنگره میکربشناسی ایران |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | |
| شهر محل برگزاری کنگره/ همایش | تهران |
| سال انتشار/ ارائه شمسی | 1399 |
| سال انتشار/ارائه میلادی | 2020 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1399/05/27 الی 1399/05/30 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | www.ism.ir |
| آدرس علمی (Affiliation) نویسنده متقاضی | Infectious and Tropical Diseases Research Center,& Immunology Research center and Department of Microbiology & Virology , Faculty of Medicine, Tabriz University of Medical Science , Tabriz, Iran. |
| نویسنده | نفر چندم مقاله |
|---|---|
| جاوید صادقی | دوم |
| آرزو آزادی | سوم |
| سیده زهرا صادقیان مطهر | چهارم |
| مهین آهنگر اسکوئی | اول |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Absence of Cytomegalovirus in Women with breast cancer in Tabriz Background and Aim : The role of human cytomegalovirus (HCMV) in breast cancer is controversial. The aim of this study was to evaluate the expression of the immediate-early antigen (IE) of HCMV in tissue blocks in a group of women with breast cancer in Tabriz. Methods: 80 Formalin-fixed and paraffin-embedded (FFPE) tissue blocks of breast cancer and 80 non-cancerous breast tissues were obtained from the pathology laboratory in Tabriz. After the Deparaffinization and DNA extraction, the IE-antigen of HCMVgenome was used as the primer for the detection of HCMV in all samples by PCR. Results: In our study, 66.3% of all cases and 82.8% of the controls were under 50 years of age. Fibrocystic lesions (71.3%) and grade II invasive ductal carcinoma (57.5%) were the most common in the control and case groups, respectively. All of 80 breast cancer samples and all non- cancerous samples were negative for the IE – antigen of HCMV gene. Conclusion: No relationship was seen between breast cancer and HCMV in this study. However, the controversy on the role of HCMV in breast cancer still remains Keywords: Breast cancer, FFPE, Human cytomegalovirus, immediate early antigen, Tabriz. |
| کلمات کلیدی | Breast cancer, FFPE, Human cytomegalovirus, immediate early antigen, Tabriz. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Bookl_Webinar.pdf | 1399/05/28 | 2396236 | دانلود |
| Ism_certificate.pdf | 1399/06/04 | 196495 | دانلود |