Optimisation of CT scan parameters to increase the accuracy of gross tumour volume identification in brain radiotherapy
Optimisation of CT scan parameters to increase the accuracy of gross tumour volume identification in brain radiotherapy
نویسندگان: داود خضرلو , محمد محمدزاده , کوثر استاک , ناهیده قره آغاجی , توحید مرتضی زاده , رحیم ختیال
کلمات کلیدی: brain radiotherapy; CT image quality; CT simulation; tumour contouring
نشریه: 21391 , 2 , 19 , 2020
| نویسنده ثبت کننده مقاله |
داود خضرلو |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
دانشکده پیراپزشکی |
| کد مقاله |
73246 |
| عنوان فارسی مقاله |
Optimisation of CT scan parameters to increase the accuracy of gross tumour volume identification in brain radiotherapy |
| عنوان لاتین مقاله |
Optimisation of CT scan parameters to increase the accuracy of gross tumour volume identification in brain radiotherapy |
| ناشر |
6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
Journal of Radiotherapy in Practice |
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Abstract
Aim: This study aimed to optimise computed tomography (CT) simulation scan parameters to
increase the accuracy for gross tumour volume identification in brain radiotherapy. For this
purpose, high-contrast scan protocols were assessed.
Materials and methods: A CT accreditation phantom (ACR Gammex 464) was used to optimise
brain CT scan parameters on a Toshiba Alexion 16-row multislice CT scanner. Dose, tube
voltage, tube current–time and CT dose index (CTDI) were varied to create five image quality
enhancement (IQE) protocols. They were assessed in terms of contrast-to-noise ratio (CNR),
signal-to-noise ratio (SNR) and noise level and compared with a standard clinical protocol.
Finally, the ability of the selected protocols to identify low-contrast objects was examined based
on a subjective method.
Results: Among the five IQE protocols, the one with the highest tube current–time product
(250 mA) and lowest tube voltage (100 kVp) showed higher CNR, while another with a tube
current–time product of 150 mA and a tube voltage of 135 kVp had improved SNR and lower
noise level compared to the standard protocol. In contouring low-contrast objects, the protocol
with the highest milliampere and lowest peak kilovoltage exhibited the lowest error rate (1%)
compared to the standard protocol (25%).
Findings: CT image quality should be optimised using the high-dose parameters created in this
study to provide better soft tissue contrast. This could lead to an accurate identification of gross
tumour volume recognition in the planning of radiotherapy treatment.
Introduction |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| Article.pdf | 1399/05/27 | 399576 | دانلود |