| Ceramic based structures are commonly applied in the regeneration of hard tissues like bone and teeth because of their similar structure as well as great biocompatibility. Hydroxyapatite (HA) has great biocompatibility, bioactivity and, bio-resorbability, so it is utilized in the repair of injured bone or tooth. Gelatin possesses great emulsifying properties, film-forming features, and excellent water-binding capacity. These properties enable extensive applications in many fields, such as biomedical materials, food, pharmaceutical, and cosmetic industries. HA-gelatin nanocomposite films were prepared and investigated in this study. The results showed relatively monodisperse HA nanoparticles with a mean particle size of 298.40 nm that were mainly pseudo-sphere in morphology. The results also showed the negative values of the zeta potential for the HA nanoparticles (-3.06 mv) and HA-gelatin nanocomposite films (-5.96 mv). The obtained physicochemical properties for the prepared structures suggested them as promising materials in bone-related drug delivery systems or in bone and teeth tissue engineering. |