The potentials of immune checkpoints for the treatment of blood malignancies
The potentials of immune checkpoints for the treatment of blood malignancies
نویسندگان: محسن علیزاده , علی صفرعلیزاده , خلیل حاجی اصغرزاده , امیر باغبانزاده , بهزاد برادران
کلمات کلیدی: Immune Checkpoint; Cancer Treatment; Blood Cancers; Human Immune System
نشریه: 8336 , 2020 , 153 , 2020
| نویسنده ثبت کننده مقاله |
بهزاد برادران |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات ایمونولوژی |
| کد مقاله |
73013 |
| عنوان فارسی مقاله |
The potentials of immune checkpoints for the treatment of blood malignancies |
| عنوان لاتین مقاله |
The potentials of immune checkpoints for the treatment of blood malignancies |
| ناشر |
8 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Review Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Immune checkpoints are the regulators of the immune system, which include stimulatory and
inhibitory receptors. They play substantial roles in the maintenance of immune system
homeostasis and the prevention of autoimmunity and cancer. In the current review, immune
checkpoints roles are surveyed in the initiation, progression, and treatment of blood
malignancies. The significant roles of immune checkpoints are discussed as clinical markers in
the diagnosis and prognosis of a plethora of blood malignancies and also as potential targets for
the treatment of these malignancies. It could be concluded that the regulation of immune
checkpoints in various blood cancers can be employed as a novel strategy to obtain effective
results in leukemia treatment and introduce immune checkpoint inhibitors as sufficient weapons
against blood cancers in the future. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| 418-The potentials of immune checkpoints for the treatment of blood.pdf | 1399/07/14 | 5634545 | دانلود |
| The potentials of immune checkpoints.jpg | 1399/07/14 | 513424 | دانلود |