چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Objective: Leptin/adiponectin (L/A) ratio is considered a pre-dicting factor of metabolic syndrome (MetS) and its related mor-bidities. In the present study, we determined the association of serum L/A ratio with MetS parameters in apparently healthy Ira-nian adults. Material and Methods: This cross-sectional study was conducted on 150 apparently healthy adults aged 25 to 50 years, who were selected by random sampling from different medical centers of Tabriz city, Iran. Our criteria for being a he-althy individual were based on self-report of the participants. Anthropometric measures, fasting blood sugar (FBS) and lipid profile, systolic and diastolic blood pressure (SBP and DBP), and fasting serum leptin and adiponectin levels were measured. Re-sults: There were significant differences (p<0.05) in weight, he-ight, waist circumference (WC), SBP, triglyceride (TG), high-density lipoprotein-cholesterol (HDL-C), serum leptin con-centration, and L/A ratio between males and females. Univariate linear regression model revealed a significant positive associa-tion of serum leptin concentration with WC (p=0.024) and FBS (p=0.046). A similar result was obtained using the multiple reg-ression model after adjusting for confounding factors (p<0.001 and p=0.045). A significant positive correlation was found bet-ween the L/A ratio and WC (p=0.010) in the adjusted model. However, no significant association was observed between adi-ponectin and MetS indices. Conclusion: Our findings indicated a significant positive association of serum leptin concentration with WC and FBS and between L/A ratio and WC in apparently healthy adults. Therefore, compared to adiponectin, leptin, and L/A ratio could be useful predictors of MetS. |
| نویسنده | نفر چندم مقاله |
|---|---|
| علی طریقت اسفنجانی | اول |
| مهرانگیز ابراهیمی ممقانی | سوم |
| سودا صالح قدیمی | دوم |
| محمد اصغری جعفرآبادی | چهارم |
| جلال مولودی | ششم |
| وحید ملکی | هفتم |
| حسین امیدی مجارشین | هشتم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 988430312251115.pdf | 1399/05/25 | 438971 | دانلود |
