Clinical characteristics and long-term outcome of Takayasu arteritis in Iran: a multicentre study
Clinical characteristics and long-term outcome of Takayasu arteritis in Iran: a multicentre study
نویسندگان: آیدا مالک مهدوی , نادره رشتچی زاده , حدیثه کاوندی , مهرزاد حاج علیلوی بناب , سوسن کلاهی , محمد رضا جعفری نخجوانی , علی اصغر ابراهیمی چهارم , سید مصطفی سید مردانی , علیرضا خبازی اسکویی
کلمات کلیدی: Takayasu arteritis, Birmingham Vasculitis Activity Score (BVAS), Indian Takayasu Clinical Activity Score (ITAS), Vasculitis
Damage Index (VDI), outcome, remission, Iran.
نشریه: 55493 , 4 , 50 , 2020
| نویسنده ثبت کننده مقاله |
علیرضا خبازی اسکویی |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
بیماری های بافت همبند |
| کد مقاله |
72697 |
| عنوان فارسی مقاله |
Clinical characteristics and long-term outcome of Takayasu arteritis in Iran: a multicentre study |
| عنوان لاتین مقاله |
Clinical characteristics and long-term outcome of Takayasu arteritis in Iran: a multicentre study |
| ناشر |
11 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
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| Background/aim: This study aimed to evaluate the demographic, clinical, angiographic and prognostic characteristics of Takayasu
arteritis (TA) in Iran.
Materials and methods: A total of 75 patients with TA based on the American College of Rheumatology 1990 criteria for TA
classification referred to the Rheumatology Centres, were followed-up from 1989 to 2019. Demographic, clinical, angiographic and
prognostic characteristics were collected at baseline and last visit.
Results: The mean age was 31.9 ± 9.8 years at the disease onset. Female to male ratio was 14. The median latency in diagnosis was 24
months. Pulse discrepancy in the arms, blood pressure discrepancy in the arms, limb claudication, hypertension and constitutional
symptoms were the most common clinical features. The most common angiographic type at the time of diagnosis was Type I (42.7%).
The most frequent arterial lesion was stenosis (89.4%). Subclavian, carotid and aortic arteries were the most commonly involved arteries.
New lesions developed in 28.6% of patients during the 5.25-year follow-up. Vasculitis-induced chronic damage was observed in all
patients. Disease activity decreased and vascular damage remained stable throughout the follow-up period.
Conclusions: The clinical features and angiographic type of TA in Iran are different from most Asian countries. Differences in
angiographic and clinical features may lead to delayed diagnosis. The issue of delay in diagnosis should create awareness among health
care providers that TA is not a very rare disease in Iranians and failure to pay attention to warning symptoms may delay the diagnosis. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| sag-50-4-9-1910-19.pdf | 1399/04/07 | 734668 | دانلود |