چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Previous studies have suggested that taurine has hypoglycemic and hypolipidemic efects on experimental diabetic models. Therefore, this clinical trial was designed to explore the impacts of taurine supplementation on glycemic control and lipid profle in the patients with T2DM. This study was conducted on 45 patients with T2DM in Tabriz Sheikhor-raees Polyclinic and Imam-Reza Hospital Endocrine Center. Subjects were randomly divided into taurine and placebo groups. Accordingly, the taurine group (n = 23) received taurine 3000 mg/daily and the placebo group (n = 22) took crystalline microcellulose/ daily for the duration of 8 weeks. At baseline and after the trial completion, fasting blood samples were obtained from the patients to assess the glycemic indicators and lipid profle. Independent t test, paired t test, Pearson’s correlation, and analysis of covariance was used for analysis. At the end of the study, levels of FBS (p = 0.01), insulin (p = 0.01), HOMA-IR (p = 0.003), TC (p = 0.013), and LDL-C (p = 0.041) signifcantly decreased in the taurine group compared to the placebo group. In addition, there was no signifcant changes in HbA1c, triglyceride, HDL-C, anthropometric indicators or dietary intakes by passing 8 weeks from the intervention. In conclusion, the fndings of the current study indicated that taurine supplementation (3000 mg/day) for 8 weeks could improve the glycemic indexes and lipid profles including TC and LDL-C in the patients with T2DM. |
| نویسنده | نفر چندم مقاله |
|---|---|
| وحید ملکی | اول |
| فاطمه اسماعیلی | دوم |
| محمد علی زاده | سوم |
| رضا مهدوی | چهارم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| AMA.fin.pdf | 1399/04/01 | 942750 | دانلود |
| Capture.PNG | 1399/04/01 | 106163 | دانلود |
| Capture2.PNG | 1399/04/01 | 102342 | دانلود |
