چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Objectives: Adenosine has an analgesic and anti-infammatory role and its injections are used for perioperative pain management. We aimed to study efcacy of intrathecal injection of adenosine for post-operative radicular pain after lumbar discectomy. Forty patients with unilevel lumbar discectomy who had radicular lower limb pain were treated by 1000 micrograms of intrathecal injection of adenosine in this single-arm prospective open-label trial between November 2015 to October 2016. Radicular pain severity using visual analogue scale (VAS) and pain killer consumption per day were assessed during a 3 months follow up period. Results: Radicular pain severity was signifcantly reduced in 3 month follow-up period in comparison to the baseline (F=19,760, df=2.53, p-value<0.001). Further, painkiller medication consumption rate in average during 3 month follow-up period after injection was signifcantly lower in comparison to baseline (F=19.244, df=1.98, p-value<0.001). This study suggests that intrathecal injection of 1000 micrograms adenosine is a safe and efective method for postoperative neuropathic pain management after uni-level disk surgeries. Trial registration IRCT201608171772N20, Retrospectively registered on 2016-08-28 |
| نویسنده | نفر چندم مقاله |
|---|---|
| داود آقا محمدی | اول |
| محمود عیدی | دوم |
| علیرضا پیش گاهی | سوم |
| اعظم اسمعیل نژاد | چهارم |
| ندا دولت خواه | پنجم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Aghamohammadi_et_al-2020-BMC_Research_Notes.pdf | 1399/03/24 | 1323022 | دانلود |
