Effect of allopurinol in the prevention of contrast-induced nephropathy in patients undergoing angioplasty: randomized clinical trial
Effect of allopurinol in the prevention of contrast-induced nephropathy in patients undergoing angioplasty: randomized clinical trial
نویسندگان: هاله بوداغ , زهرا اصفهانی , بیتا امیری , ناصر اصلان آبادی , علی حیدری
کلمات کلیدی: Percutaneous Coronary Intervention, Allopurinol, Angioplasty
نشریه: 0 , 4 , 7 , 2019
| نویسنده ثبت کننده مقاله |
هاله بوداغ |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
دانشکده پزشکی |
| کد مقاله |
72509 |
| عنوان فارسی مقاله |
Effect of allopurinol in the prevention of contrast-induced nephropathy in patients undergoing angioplasty: randomized clinical trial |
| عنوان لاتین مقاله |
Effect of allopurinol in the prevention of contrast-induced nephropathy in patients undergoing angioplasty: randomized clinical trial |
| ناشر |
5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
Journal of research clinical medicine |
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح چهار – سایر سایت های تخصصی |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Allopurinol could decrease the undesirable effects of free radicals and then prevent contrast induced nephropathy (CIN). Therefore, it may be useful for reducing the ischemia-reperfusion induced nephropathy and inhibiting nitric oxide synthesis produced in CIN. This study was performed aimeing to determine the effect of allopurinol in the prevention of CIN in patients undergoing angioplasty.
In this randomized clinical trial, 100 patients (50 cases as the intervention group receiving allopurinol 300 mg one day and one hour before angiography and 50 cases as the control group) were evaluated. CIN was considered if the serum creatinine (SCr) value was increased 25% in relation to its basic value. Additionally, the prevalence of CIN was evaluated. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| jarcm-7-118.pdf | 1399/03/22 | 1001129 | دانلود |