چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| miRNAs are a group of non-coding RNAs that have regulatory functions in post-transcriptional gene expression. These molecules play a fundamental role in cellular processes, for instance cell proliferation, apoptosis, migration, and invasion. Scientific investigations have previously established that miRNAs can either promote or suppress tumor development by mediating different signaling pathways. miR-139-5p, located on chromosome 11q13.4, has been examined extensively in cancers. Studies have demonstrated that miR-139-5p might be an attractive cancer biomarker. Herein, we will review how miR-139-5p acts in cancer diagnosis, prognosis, and therapy, as well as elucidating its major target genes and associated signaling pathways. |
| نویسنده | نفر چندم مقاله |
|---|---|
| مسعود نوری وسکه | دوم |
| زهرا حسن پور | سوم |
| امیر باغبانزاده | چهارم |
| منیره حلیمی | پنجم |
| هاله رضائی | ششم |
| بهزاد برادران | هفتم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Diagnostic, prognostic, and therapeutic significance of miR-139-5p in.pdf | 1399/03/21 | 2394881 | دانلود |
